Check out recent publications and news items featuring FNIH programs and activities.
July 2020
- Accelerating development of SARS-Cov-2 vaccines: The role for controlled human infection models. Deming, M. E., Michael, N. L., et al. NEJM (July 1, 2020)
June 2020
- Integrated urine proteomics and renal single-cell genomics identify an IFN-γ response gradient in lupus nephritis. Fava A., et al. JCI insight. 18 June 2020. https://doi.org/10.1172/jci.insight.138345.
May 2020
- Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): An Unprecented Partnership for Unprecedented Times. Collins F S, Stoffels P. JAMA Network (May 18, 2020)
- Association of knee OA structural phenotypes to risk for progression: a secondary analysis from the Foundation for the National Institutes of Health Osteoarthritis Biomarkers study (FNIH). Roemer F W., Collins J E., et al. Osteoarthritis and Cartilage (May 17, 2020)
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Remote digital monitoring in clinical trials in the time of COVID-19. Goldsack J C, Izmailova E S, Menetski J P, Hoffmann S C, Groenen P M A, Wagner J A. Nature Reviews Drug Discovery (May 14, 2020)
- For more information on the Biomarkers Consortium Remote Digital Monitoring Workshop, click here.
April 2020
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Study shows immunotherapy prior to surgery may help destroy high-risk breast cancer. Yale University (April 28, 2020)
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For more information on the I-SPY clinical trial, click here.
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For more information on the I-SPY clinical trial, click here.
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Notch signalling drives synovial fibroblast identity and arthritis pathology. Wei, K., Korsunsky, I., et al. Nature (2020)
- For more information on the AMP-RA/Lupus Project, click here.
March 2020
- Disruptive innovation in rheumatology: new networks of global public-private partnerships are needed to take advantage of scientific progress. Huizinga TWJ, et al. Annals of the Rheumatic Diseases 2020;0:1–3. doi:10.1136/annrheumdis-2019-216846
February 2020
- Lung-MAP: A five-year recap on the first master protocol trial in cancer research. Herbst R S, et al. The Cancer Letter 2020
2019
August 2019
- Traditional and Digital Biomarkers: Two Worlds Apart? Babrak L.M. Menetski J. et al. Digital Biomarkers 2019;3-92-102. doi: 10.1159/000502000
July 2019
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Brief Report: SWOG S1400C (NCT02154490)-A Phase II Study of Palbociclib for Previously Treated Cell Cycle Gene Alteration Positive Patients with Stage IV Squamous Cell Lung Cancer (Lung-MAP Sub-study). Edelan MJ, Redman MW, Albai KS, et al. 2019. Journal of Thoracic Oncology. doi: 10.1016/j.jtho.2019.06.027.
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For more information on the Lung-MAP project, click here.
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June 2019
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Brief Report: SWOG 1400D (NCT02965378), a Phase II Study of Fibroblast Growth Factor Receptor Inhibitor AZD4547 in Previously-treated Patients with Fibroblast Growth Factor Pathway-Activated Stage IV Squamous Cell Lung Cancer (Lung-MAP Sub-Study). Aggarwal C, Redman M W, Primo L N Jr, et al. 2019. Journal of Thoracic Oncology. doi: 10.1016/j.jtho.2019.05.041.
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For more information on the Lung-MAP project, click here.
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May 2019
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A Phase II Study of GDC-0032 (Taselisb) for Previously Treated PI3K-Positive with Stave IV Squamous Cell Lung Cancer (Lung-MAP Sub-Study). Langer CJ, Redman MW, Wad JL 3rd, et al. 2019. Journal of Thoracic Oncology. doi: 10.1016/j.jtho.2019.05.029.
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For more information on the Lung-MAP project, click here.
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Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Zhang F, Wei K, Slowikowski K, et al. 2019. Nature Immunology.doi: 10.1038/s41590-019-0378-1.
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For more information on the AMP-RA/Lupus project, click here.
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March 2019
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Seasonal Food Insecurity in Haydom, Tanzania, Is Associated with Low Birthweight and Acute Malnutrition: Results from the MAL-ED Study. Rogawski McQuade ET, Clark S, Bayo E, Scharf RJ, et al. 2019. Seasonal Food Insecurity in Haydom, Tanzania, Is Associated with Low Birthweight and Acute Malnutrition: Results from the MAL-ED Study. Am J Trop Med and Hygiene.
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Longitudinal Assessment of Antibiotic Resistance in Fecal Escherichia coli in Tanzanian Children.Fleece M, Nshama R, Walongo T, Kimathi C, et al. 2019. Longitudinal assessment of antibiotic resistance in fecal Escherichia coli in Tanzanian children. Am J Trop Med and Hygiene. doi: 10.4269/ajtmh.18-0789
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For more information on the MAL-ED Project, click here.
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January 2019
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Evidence-Based Study Design for Hospital Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia. Talbot G H, Das A, Cush S, Dane A, Wible M, Echols R, Torres A, Cammarata S, Rex J H, Powers J H, Fleming T, Loutit J, Hoffmann S. 2019. Foundation for the National Institutes of Health Biomarkers Consortium HABP/VABP Project Team, Evidence-Based Study Design for Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia, The Journal of Infectious Diseases, , jiy578.
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For more information on the HABP/VABP Project, click here.
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To learn more about the programs we support, click here.
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