Overview

Today, there are no approved therapies to treat Long COVID or its symptoms. This has left millions of patients suffering and waiting for answers.

A new program is working to change that. Researching COVID to Enhance Recovery–Treating Long COVID (RECOVER-TLC) is an FNIH initiative led by the National Institute of Allergy and Infectious Diseases (NIAID). Our goal is to unite the scientific and patient communities in finding new approaches to address Long COVID.

RECOVER-TLC will apply lessons learned from an earlier program, RECOVER, launched in 2021 by the National Institutes of Health (NIH).

As an important first step, we are inviting the community to help identify promising therapeutic approaches. This could include proposed drugs, devices, or other therapeutic agents targeted at alleviating symptoms associated with Long COVID. We encourage all individuals – patients, caregivers, scientists, etc. – to share their ideas.

Goals
  • Assess new ideas, identify potential therapeutics, and execute innovative study designs.

  • Provide ongoing scientific and community engagement

  • Provide additional clinical trial capacity, building upon existing RECOVER trial sites

RECOVER-TLC Workshop

More than 1,500 people gathered for the first RECOVER-TLC Workshop in Bethesda, Md., on Sept. 23, 2024. Videos of each session are available below.

Click the playlist button at the top right
of the video viewer for additional panels

RECOVER-TLC Background

RECOVER-TLC will build on the work of the RECOVER program, which is led by three NIH Institutes: The National Heart, Lung, and Blood Institute (NHLBI); NIAID; and the National Institute of Neurological Disorders and Stroke (NINDS).

RECOVER has engaged more than 30,000 people in ongoing studies and clinical trials. This has created a research engine of unprecedented scale and scope, including one of the largest and most diverse Long COVID cohorts in the world. This work has advanced our understanding and provided valuable insights into designing and conducting clinical trials to address patient-centered endpoints. Data from ongoing RECOVER trials and studies will inform RECOVER-TLC efforts.

Partners

Public-Sector Partners
  • National Center for Advancing Translational Sciences’
  • National Heart, Lung, and Blood Institute
  • National Institute for Neurologic Diseases and Stroke
  • National Institute of Allergy and Infectious Disease
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