ACTIV:
Therapeutics Working Group

TCWG focused on:

• Establishing a steering committee with relevant expertise to set criteria for and rank potential candidates submitted by industry partners for testing
• Developing a complete inventory of potential candidates with different mechanisms of action and acceptable safety profiles
• Designing, launching and openly sharing master protocols with agreed-upon endpoints, sampling and analysis for evaluating candidates
• Using novel trial designs that incorporated single control arms to enhance trial efficiency and increase enrollment and diversity of participants