The goal of ACTIV is to develop a research strategy for prioritizing and speeding development of the most promising COVID-19 vaccines and treatments.
The Therapeutics Clinical Working Group is focused on:
- Establishing a steering committee with relevant expertise to set criteria for and rank potential candidates submitted by industry partners for testing
- Developing a complete inventory of potential candidates with different mechanisms of action and acceptable safety profiles
- Designing, launching and openly sharing master protocols with agreed-upon endpoints, sampling and analysis for evaluating candidates
- Using a single control arm to enhance trial efficiency
Clinical Trial Protocols