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Displaying 51 - 75 of 90

Biomarkers Consortium – Measurable residual disease in acute myeloid leukemia (MRD in AML)
The Problem Detection of measurable residual disease (MRD) is a strong predictor of relapse in acute and chronic leukemia, but its integrat...
Biomarkers Consortium – ctDNA Quality Control Materials Project
The Problem Tumor DNA circulating in bodily fluids offers researchers a valuable tool to study, and thus to treat, cancer. Yet the wide var...
Biomarkers Consortium – CSC Scientific Symposium
The Problem cancer research is a large and diverse field, making it difficult to coordinate efforts across its many subfields, which are fo...
Biomarkers Consortium – The Performance of Novel Cardiac Biomarkers in the General U.S. Population
The Problem Cardiovascular disease is one of the most lethal conditions in the United States, yet Researchers lack the tools needed to asse...
Biomarkers Consortium – I-SPY TRIAL-2 (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging and MoLecular Analysis): An Adaptive Breast Cancer Trial Design in the Setting of Neoadjuvant Chemotherapy
Overview The I-SPY 2 trial was setup to accelerate the pace of qualifying effective novel agents for breast cancer by testing new agents in...
Biomarkers Consortium – Inflammatory Markers for Early Detection and Subtyping of Neurodegenerative and Mood Disorders
The Problem Neurodegenerative and psychiatric conditions such as Alzheimer’s disease and Major Depressive Disorder present very differentl...
Biomarkers Consortium – Mucosal Healing in UC: Definition, Treatment Target and Clinical Endpoints
The Problem Mucosal healing is an important outcome in clinical trials of drugs to treat ulcerative colitis, yet Researchers lack a standar...
Biomarkers Consortium – NiP-Metastatic Prostate Cancer
Overview Metastatic castration-resistant prostate cancer (mCRPC) is the second leading cause of cancer death of American men. Over 80% of t...
Biomarkers Consortium – Plasma Aβ as a Predictor of Amyloid Positivity in Alzheimer’s Disease
The Problem Early treatment of Alzheimer’s disease requires early diagnosis. Yet available methods to diagnose early AD are expensive or ...
Biomarkers Consortium – PROGRESS OA: Clinical Evaluation and Qualification of Osteoarthritis Biomarkers
Overview The Biomarkers Consortium’s PROGRESS OA - Clinical Evaluation and Qualification of Osteoarthritis Biomarkers Project is the seco...
Biomarkers Consortium – Remote Digital Monitoring and Patient-Centric Medical Product Development
The Problem Researchers and caregivers can collect patient data using novel remote digital monitoring technology when patients are not in t...
Biomarkers Consortium – Clinical Evaluation and Qualification of Translational Kidney Safety Biomarkers
The Problem When conducting clinical trials of any drugs that could cause acute kidney injury, Researchers need biomarkers that can detect ...
Age-Related Eye Disease Study 2 (AREDS2) Ancillary Study
Overview The project was completed in 2013. The Age-Related Eye Disease Study 2 (AREDS2) overseen by the National Eye Institute (NEI) examin...
African Centers of Excellence in Bioinformatics
The African Centers of Excellence in Bioinformatics is a strategic public-private partnership of the National Institute of Allergy and Infec...
Alzheimer’s Disease Neuroimaging Initiative 3 (ADNI 3)
The Problem Individuals with Alzheimer’s disease often do not show symptoms during the early stages of disease, limiting clinicians’ ab...
Biomarkers Consortium – Bone Quality Project
The Problem Patients with osteoporosis, other bone diseases or increased risk for bone fractures have diminished bone strength and quality,...
Amgen Scholars Program at NIH
Amgen Scholars Program at NIH" In 2015, the NIH became one of 24 leading institutions taking part in the Amgen Scholars Prog...
Biomarkers Consortium – Developing Endpoints for Clinical Trials in Community Acquired Bacterial Pneumonia (CABP) and Acute Skin and Skin Infections (ABSSSI)
The Problem To develop effective treatments for community-acquired bacterial pneumonia and acute bacterial skin and skin structure infection...
Adam J. Berry Memorial Fund
Overview Since 2003, the Adam J. Berry Memorial Fund has supported travel  for early-career Australian scientists to work at the NIH, in p...
ACTIV Seminar Series: Post-Acute Sequelae of SARS-CoV-2
Overview COVID patients who experience lingering symptoms for months or weeks after initial recovery are said to have post-acute sequelae o...
Accelerating Medicines Partnership® Program – Rheumatoid Arthritis, Systemic Lupus Erythematosus
The Problem Autoimmune disorders such as Rheumatoid Arthritis and Systemic Lupus Erythematosus are biologically complex; understanding the ...
Global Pandemic Treaty
Edmond J. Safra Family Lodge
GeneConvene Global Collaborative
The Deeda Blair Research Initiative for Disorders of the Brain 
The Deeda Blair Research Initiative was created to improve the diagnosis and treatment of severe mental illness, including mood disorders, a...

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