Programs

To tackle the human health challenges that face the world today, the FNIH develops collaborations with top experts from government, industry, academia and the not-for-profit sector and provides a neutral environment where we can work productively toward a common goal.

Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV)

Coordinated by the Foundation for the National Institutes of Health (FNIH), ACTIV brings NIH together with its sibling agencies in the Department of Health and Human Services, other government agencies, representatives from academia, philanthropic organizations and more than 15 biopharmaceutical companies to develop a coordinated research strategy for prioritizing and speeding the development of COVID-19 vaccines and treatments.

Pandemic Response Fund

Through the FNIH Pandemic Response Fund, donors support the National Institutes of Health's (NIH’s) efforts to speed COVID-19 vaccine and treatment research and prepare the United States for future pandemics.

2020 National Research Summit on Care, Services & Supports for Persons with Dementia and their Caregivers

The National Institute on Aging (NIA) is hosting its 2nd National Research Summit on Care, Services, and Supports for Persons with Dementia and Their Caregivers on March 24-25, 2020 in Bethesda, Maryland. Through the Summit, the NIA seeks to accelerate the development, evaluation, translation, implementation, and scaling up of evidence-based and evidence-informed services for individuals with dementia, their family and caregivers.

NINDS Healthcare Disparities in Tribal Communities Summer Internship Program

The NINDS Healthcare Disparities in Tribal Communities (HDTC) Summer Internship Program (SIP) is a student research training program in brain and nervous system research. The program focuses on neurological disorders and healthcare disparities and seeks to provide research experiences and career development opportunities for Native American students, along with students from other underrepresented communities.

Understanding the Mechanisms of Intravenous BCG-Induced Protection Against TB in NHP (TB Vaccine)

Two billion people worldwide are infected with Mycobacterium tuberculosis (Mtb) resulting in 10 million cases of clinical disease and 1.5 million deaths each year. The hurdles for developing a highly protective and durable vaccine against Mtb require addressing four central tenets of T cell immunology – magnitude, quality, breadth, and location of the response. These specific elements of the problem will be addressed by focusing on how altering the route of vaccination using a whole attenuated organism vaccine substantially increases immune responses and protection in a rigorous non-human primate model of Mtb infection.

Gene Drive Research-Related Activities

Gene drive is a mechanism that can promote the preferential inheritance of a beneficial genetic trait, thereby increasing its prevalence in a population. A variety of gene drive mechanisms occur in nature that can cause specific genetic elements to spread throughout populations in varying degrees. Researchers have long sought to harness these naturally occurring gene drive mechanisms to prevent the transmission of mosquito or other insect-borne diseases that pose some of society's most intractable public health problems.

Support functions for development of new technologies for controlling transmission of mosquito-borne diseases

The project provides the FNIH management and advisory services for research programs seeking to develop new cost-effective and sustainable biologic strategies for controlling mosquito-borne infections like malaria and dengue fever.

Single-Cell Transcriptomic Analysis of HIV Reservoirs before and After Systemic Interleukin-2 (IL-2) Therapy
Comprehensive Cellular Vaccine Immune Monitoring Consortium

A collaborative program that provides standardized and research level assays for clinical and pre-clinical HIV vaccine trials.

SHORTEN-TB

SHORTEN-TB will build on lessons learned from the HIT-TB program to identify leads that have the greatest potential to comprise drug regimens that will significantly reduce the duration of chemotherapy for tuberculosis.